This article discusses emerging Israeli technologies aimed at improving in vitro fertilization (IVF) outcomes as couples increasingly opt for assisted reproductive methods. Key innovations include the Lioness device for preventing preterm birth, the AI-enhanced Fertilane platform, and various solutions like hyaluronic acid incorporation, as well as automated sperm selection and embryo assessment tools. These advancements illustrate the ongoing commitment to enhancing reproductive health and family planning solutions.
Increasingly, couples across the globe are choosing to start families later in life, resulting in a heightened reliance on assisted reproductive technologies, particularly in vitro fertilization (IVF). To assist individuals in understanding this complicated landscape, IVFBabble introduced World Fertility Day in 2018, observed on November 2, to promote awareness regarding fertility preservation, reproductive health, and family planning. In anticipation of World Fertility Day 2024, ISRAEL21c has curated a compilation of groundbreaking Israeli advancements in fertility technology. One such development is the Lioness device created by PregnanTech in northern Israel, which aims to address high preterm birth rates associated with IVF. This non-surgical device is implanted through a swift outpatient procedure and is designed to remain stable throughout pregnancy, featuring a self-release mechanism for labor. Another innovative solution comes from FertilAI located in Givatayim. Their platform, Fertilane, employs artificial intelligence to accurately predict ovulation cycles and provide personalized treatment recommendations, potentially increasing the retrieval of viable eggs by 30% and enhancing clinical pregnancy rates by 5-8%. Research from the Kaplan Medical Center and Hebrew University suggests that incorporating hyaluronic acid, traditionally used in cosmetics, into the embryo culture medium can also greatly improve IVF success rates. According to Dr. Devorah Heymann, exposing embryos to hyaluronic acid for over ten minutes prior to transfer has shown an increase in birth likelihood from 32% to 39%. The Tel Aviv startup BAIBYS is revolutionizing sperm selection for IVF with the introduction of AI and micro-robotics. This approach seeks to streamline the sperm selection process, reducing both time and costs while increasing success rates and minimizing birth defects. Recently, BAIBYS secured $4.5 million in Series A funding, demonstrating investor confidence in its technology. FertiliFit, based in Haifa, employs advanced data analytics and machine learning to refine IVF treatments, aiming to enhance success rates and decrease the number of cycles required for egg extraction. Founded by Michal Jacob, who experienced IVF challenges first-hand, the startup focuses on creating personalized algorithms for treatment adaptations. Fairtility, a rapidly growing Tel Aviv company, has raised nearly $20 million to develop CHLOE EQ, an AI-based embryo quality assessment tool. This product aims to significantly improve pregnancy outcomes by providing early and data-driven assessments of embryo quality and is expected to expand its functionalities beyond embryo evaluation in the future. Embryonics is another innovative firm from Tel Aviv, leveraging AI to facilitate improvements in embryo selection and noninvasive genetic analysis. Founded in 2018 by Yael Gold Zamir, the company strives to simplify the IVF process, making it more cost-effective and widely accessible. Lastly, AIVF offers a comprehensive software platform that employs AI to automate and digitize IVF clinic operations. With over $25 million raised since its establishment, AIVF’s clinical trials in Europe and the United States have shown promise in reducing the number of IVF cycles necessary for conception and enhancing prediction accuracy by 48%.
The landscape of fertility treatments is evolving, particularly as societal trends indicate a shift towards delayed family planning among couples. As assisted reproductive technologies like IVF become increasingly integral to achieving successful pregnancies, the demand for innovative solutions to improve these processes grows. In this context, Israeli technology firms are at the forefront, developing new devices and platforms designed to address the common challenges faced in fertility treatments. The establishment of World Fertility Day serves to heighten public awareness and education regarding these advancements.
The advancements in fertility technology by Israeli companies highlight a significant shift towards enhancing IVF success rates and reducing complications associated with assisted reproduction. From devices that address preterm birth risks to platforms utilizing AI for personalized treatment plans, these developments reflect a concerted effort toward improving the overall experience for individuals facing fertility challenges. As technology continues to evolve, the field of reproductive health is expected to see further progressive changes.
Original Source: www.israel21c.org
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